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Items: 3

1.

Transcriptome analysis of patient-derived xenograft models of HER2+ breast cancer brain metastases

(Submitter supplied) To gain insights into tumor heterogeneity in anti-cancer drug responses of patient-derived xenograft models of HER2+ breast cancer brain metastases, we performed transcriptome gene expression profiling by Ion AmpliSeq™ Transcriptome sequencing that targets more than 20,000 human genes. Our data found that all anti-cancer drugs responders have significantly higher expression levels of AKT-mTOR-dependent signature genes as compared to the non-responders, suggesting that most HER2+ breast cancer brain metastases are depend on the AKT-mTOR pathway
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17303
10 Samples
Download data: XLS
2.

Ion Torrent Proton (Homo sapiens)

Platform
Accession:
GPL17303
ID:
100017303
3.

PDX_TX_DFBM507_rep2

Organism:
Homo sapiens
Source name:
HER2+ breast cancer brain metastases
Platform:
GPL17303
Series:
GSE80722
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Sample
Accession:
GSM2134303
ID:
302134303
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db=gds|term=GSM2134303[Accession]|query=1|qty=2|blobid=MCID_66a1bd4b56cb0a044eb12b29|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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