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Items: 3

1.

Different promoter affinities account for specificity in MYC-dependent gene regulation

(Submitter supplied) Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests gene-specific regulation. Here, we have explored the hypothesis that specific gene expression profiles arise since promoters differ in affinity for MYC and high-affinity promoters are fully occupied by physiological levels of MYC. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL10999
22 Samples
Download data: TXT, WIG
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

ChIPseq_input_siCTR_siMYC

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL18573
Series:
GSE77356
Download data: WIG
Sample
Accession:
GSM2131217
ID:
302131217
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db=gds|term=GSM2131217[Accession]|query=1|qty=2|blobid=MCID_669d6a5157bd0c1190a144a1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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