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Items: 4

1.

MLL1 is essential for the senescence-associated secretory phenotype [ChIP-Seq]

(Submitter supplied) Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the senescence-associated secretory phenotype (SASP). Previous observations link the transcription-associated methyltransferase and oncoprotein MLL1 to the DDR, leading us to investigate the role of MLL1 in SASP expression. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
16 Samples
Download data: BW
Series
Accession:
GSE78141
ID:
200078141
2.

MLL1 is essential for the senescence-associated secretory phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the senescence-associated secretory phenotype (SASP). more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL11154
20 Samples
Download data: BW
Series
Accession:
GSE78142
ID:
200078142
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

H3K4me3 WT Control (SC H3K4me3)

Organism:
Homo sapiens
Source name:
IMR90 Lung Fibroblasts
Platform:
GPL18573
Series:
GSE78141 GSE78142
Download data: BW
Sample
Accession:
GSM2067930
ID:
302067930
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Supplemental Content

db=gds|term=GSM2067930[Accession]|query=1|qty=2|blobid=MCID_661daac3d4af9b2089327d9b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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