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Items: 3

1.

Direct reprogramming of hepatic myofibroblasts into hepatocytes in vivo attenuates liver fibrosis

(Submitter supplied) Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine, but until now has only been shown in culture settings. Here, we describe in vivo iHep formation using transcription factor induction and genetic fate tracing in mouse models of chronic liver disease. We show that ectopic expression of the transcription factors FOXA3, GATA4, HNF1A and HNF4A from a polycistronic lentiviral vector converts mouse myofibroblasts into cells with a hepatocyte phenotype. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
12 Samples
Download data: TXT
Series
Accession:
GSE76843
ID:
200076843
2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
334 Series
1 Related Platform
4120 Samples
Download data
Platform
Accession:
GPL11202
ID:
100011202
3.

Pr-mHSC, rep 3

Organism:
Mus musculus
Source name:
Pr-mHSC
Platform:
GPL11202
Series:
GSE76843
Download data: TXT
Sample
Accession:
GSM2038688
ID:
302038688
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db=gds|term=GSM2038688[Accession]|query=1|qty=2|blobid=MCID_66530be8e795547e5f76dd2c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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