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Items: 3

1.

ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression

(Submitter supplied) Human-specific KRAB-ZF proteins are putative transcription factors and correlate with human cognitive and linguistic ability. The typical KRAB-ZF protein ZNF599 has been implicated in developmental delay. However, the underlying molecular mechanism is elusive. Here, we show a specific interaction of ZNF599 with DNMT3A, but not DNMT3B or DNMT1. Using CRISPR/Cas9, we generated a ZNF599-/- cell line that shows an irregular nuclear morphology with blebbings, dents and ridges. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18460
8 Samples
Download data: TXT
Series
Accession:
GSE76129
ID:
200076129
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

HELA_WT4

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL18460
Series:
GSE76129
Download data: TXT
Sample
Accession:
GSM1974842
ID:
301974842
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db=gds|term=GSM1974842[Accession]|query=1|qty=2|blobid=MCID_6652c982e795547e5f7108a7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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