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Items: 4

1.

Dual RNA-seq – Dual RNA-seq of further sRNA mutants

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20051 GPL20050
42 Samples
Download data: CSV
Series
Accession:
GSE67952
ID:
200067952
2.

Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Sus scrofa; Mus musculus; Salmonella enterica subsp. enterica serovar Typhimurium; Homo sapiens
Type:
Expression profiling by high throughput sequencing
8 related Platforms
279 Samples
Download data
Series
Accession:
GSE60144
ID:
200060144
3.

Illumina NextSeq 500 (Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344)

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
7 Series
94 Samples
Download data
Platform
Accession:
GPL20051
ID:
100020051
4.

4 h WT replicate 3

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20051
Series:
GSE60144 GSE67952
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Sample
Accession:
GSM1967955
ID:
301967955
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