GSM1890024[Accession] - GEO DataSets

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Items: 3

Select item 2000732811.

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma (Agilent Arrays)

(Submitter supplied) Chronic active B cell receptor (BCR) signaling, a hallmark of the ABC subtype of diffuse large B cell lymphoma (DLBCL), engages the CARD11-MALT1-BCL10 (CBM) adapter complex to activates IkappaB kinase (IKK) and the classical NF-kappaB pathway. Here we show that the CBM complex includes the E3 ubiquitin ligases cIAP1 and cIAP2, which are essential mediators of BCR-dependent NF-kappaB activity in ABC DLBCL. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL13607 GPL16699
20 Samples

Download data: TXT

Series

Accession:: GSE73281

ID:: 200073281

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000166992.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...