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Items: 4

1.

Intragenic DNA methylation prevents cryptic transcription initiations on gene bodies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL16173
78 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE72856
ID:
200072856
2.

Intragenic DNA methylation prevents cryptic transcription initiations on gene bodies [CAPIP-seq]

(Submitter supplied) In mammals, DNA methylation occurs mainly at 5mC of CpG dinucleotides. The methylation on the promoter leads to the suppression of gene expression, while the functional role of gene body DNA methylation in highly expressed genes has yet to be clarified. Here, we show that the Dnmt3b-dependent intragenic DNA methylation protects the gene body from RNA Polymerase II (RNA Pol II) spurious entry and cryptic transcription initiation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
8 Samples
Download data: BEDGRAPH
Series
Accession:
GSE72852
ID:
200072852
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

CAPIP_seq_WT_rep1

Organism:
Mus musculus
Source name:
CAPIP_seq_WT
Platform:
GPL19057
Series:
GSE72852 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM1873384
ID:
301873384
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Supplemental Content

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