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Items: 4

1.

DNaseI hypersensitivity assay and ER, GR, and FoxA1 binding patterns in breast cancer cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL11154
57 Samples
Download data: BEDGRAPH
Series
Accession:
GSE72252
ID:
200072252
2.

Characterization of ER, GR, and FoxA1 binding patterns in breast cancer cells treated with either Dex or E2

(Submitter supplied) The estrogen receptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1 (FoxA1) are significant factors in breast cancer progression. FoxA1 is well-established as a pioneer factor for steroid receptor recruitment to chromatin. Here we show that ER and GR have the ability to alter the genomic response of FoxA1 to specific binding sites within the genome. These findings alter the classical understood mechanism of FoxA1 establishing a dynamic transcription factor that can be regulated by hormones.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
45 Samples
Download data: BEDGRAPH, CSV
Series
Accession:
GSE72249
ID:
200072249
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

Dex rep#2 GR ChIP-seq GH1005

Organism:
Homo sapiens
Source name:
ZR-75-1 breast cancer cell line
Platform:
GPL11154
Series:
GSE72249 GSE72252
Download data: BEDGRAPH
Sample
Accession:
GSM1858634
ID:
301858634
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Supplemental Content

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