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Items: 4

1.

Genome-wide H2B monoubiquitination regulates gene expression by coordinating H3K4me3 and H3K27me3

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL13112 GPL17021
25 Samples
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Series
Accession:
GSE72239
ID:
200072239
2.

Genome-wide H2B monoubiquitination regulates gene expression by coordinating H3K4me3 and H3K27me3 [ChIP-Seq Data Set]

(Submitter supplied) Gene body-associated monoubiquitination of H2B (H2Bub1) coupled with promoter-associated active histone modifications such as trimethylation H3 on lysine 4 (H3K4me3) and acetylation H3 on lysine 27 (H3K27ac) facilitate gene transcription. However, surprisingly, only a subset of genes is altered in their expression following knockdown of H2B ubiquitin-protein ligases RNF20 or RNF40 in human cells. In order to obtain a more complete genome- and transcriptome-wide understanding of the role of H2Bub1 in gene transcription, we generated tamoxifen-inducible Rnf40 knockout mouse embryonic fibroblasts (MEFs). more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17021 GPL19057
19 Samples
Download data: BIGWIG
Series
Accession:
GSE72237
ID:
200072237
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

H3K27me3_WT_rep2

Organism:
Mus musculus
Source name:
Mouse embryonic fibroblasts
Platform:
GPL17021
Series:
GSE72237 GSE72239
Download data
Sample
Accession:
GSM1858320
ID:
301858320
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Supplemental Content

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