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Items: 3

1.

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

(Submitter supplied) While genome sequencing has identified numerous non-coding alterations between primate species, which of these are regulatory and potentially relevant to the evolution of the human brain is unclear. Here, we annotate cis-regulatory elements (CREs) in the human, rhesus macaque and chimpanzee genome using ChIP-sequencing in different anatomical parts of the adult brain. We find high similarity in the genomic positioning of CREs between rhesus macaque and humans, suggesting that the majority of these elements were already present in a common ancestor 25 million years ago. more...
Organism:
Macaca mulatta; Homo sapiens; Pan troglodytes; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
8 related Platforms
98 Samples
Download data: BEDGRAPH, BW, NARROWPEAK, TXT
Series
Accession:
GSE67978
ID:
200067978
2.

Illumina HiSeq 2000 (Pan troglodytes)

Organism:
Pan troglodytes
18 Series
281 Samples
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Platform
Accession:
GPL16809
ID:
100016809
3.

H3K27ac Chimpanzee Brain ThalamicNuclei PT3

Organism:
Pan troglodytes
Source name:
Chimpanzee female thalamic nuclei tissue
Platform:
GPL16809
Series:
GSE67978
Download data: BEDGRAPH, BW, NARROWPEAK, TXT
Sample
Accession:
GSM1821411
ID:
301821411
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