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Items: 3

1.

Differential expression profiles of type I JAK inhibitor persistent vs. naïve MPN cells

(Submitter supplied) The type I JAK inhibitor ruxolitinib is approved for therapy of MPN patients but evokes resistance with longer exposure. Several novel type I JAK inhibitors were studied and we show that they uniformly induce resistance via a shared mechanism of JAK family heterodimer formation.Here we studied the expression profiles of SET2 cell lines persistent to several different type I JAK inhibitors in comparison to naive SET2 cells or in comparison to SET2 cells with acute exposure to ruxolitinib.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17303
24 Samples
Download data: TXT
Series
Accession:
GSE69827
ID:
200069827

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Ion Torrent Proton (Homo sapiens)

Organism:
Homo sapiens
396 Series
6218 Samples
Download data
Platform
Accession:
GPL17303
ID:
100017303

3.

SET2 cells persistent to BMS911543_replicate 1

Organism:
Homo sapiens
Source name:
SET2 cell line
Platform:
GPL17303
Series:
GSE69827
Download data
Sample
Accession:
GSM1817323
ID:
301817323

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db=gds|term=GSM1817323[Accession]|query=1|qty=2|blobid=MCID_678528887eb86f557f09d58d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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