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Items: 4

1.

BRCA1, R-loops and Recombination defects in Ewing's sarcoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Other; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL21290
79 Samples
Download data: BED, TXT
Series
Accession:
GSE68847
ID:
200068847
2.

BRCA1, R-loops and Recombination defects in Ewing's sarcoma (RNA-seq)

(Submitter supplied) Ewing’s sarcoma family of tumors (ESFT) is an aggressive pediatric bone and soft tissue cancer. It is the prototypical example of mesenchymal tumors driven by a fusion oncogene involving the ewing sarcoma break point region 1 (EWSR1) gene, most frequently– EWS-FLI1. We have discovered that loss of EWSR1 leads to accumulation of R-loops, replication stress and impaired homologous recombination, recapitulating breast cancer 1, early onset (BRCA1) deficiency. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
27 Samples
Download data: TXT
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

CHLA258 NT

Organism:
Homo sapiens
Source name:
Ewing's sarcoma CHLA258
Platform:
GPL11154
Series:
GSE68836 GSE68847
Download data: TXT
Sample
Accession:
GSM1682843
ID:
301682843
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Supplemental Content

db=gds|term=GSM1682843[Accession]|query=1|qty=2|blobid=MCID_6621def6e288b44575680fa7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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