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Items: 4

1.

Delay and restoration of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by TGF-beta pathway inhibitors: Implications for age-related macular degeneration

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL17303 GPL4133 GPL17301
54 Samples
Download data: TXT
Series
Accession:
GSE67899
ID:
200067899
2.

Reversal of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by the TGFb pathway inhibitor, A-83-01.

(Submitter supplied) Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation and inflammation to a disease of neovascular fibrosis and/or cell death. Here, we investigate how repeated wound stimulus leads to seminal changes in gene expression and the onset of a perpetual state of stimulus-independent wound response in retinal pigmented epithelial (RPE) cells, a cell-type central to the etiology of AMD. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL17303 GPL17301
10 Samples
Download data: TXT
3.

Ion Torrent Proton (Homo sapiens)

Platform
Accession:
GPL17303
ID:
100017303
4.

RPEB_P0_D32

Organism:
Homo sapiens
Source name:
Fetal RPE-Donor "B"
Platform:
GPL17303
Series:
GSE67898 GSE67899
Download data: TXT
Sample
Accession:
GSM1657678
ID:
301657678
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