GSM1657678[Accession] - GEO DataSets

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Items: 4

Select item 2000678991.

Delay and restoration of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by TGF-beta pathway inhibitors: Implications for age-related macular degeneration

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL4133 GPL17303 GPL17301
54 Samples

Download data: TXT

Series

Accession:: GSE67899

ID:: 200067899

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000678982.

Reversal of persistent wound-induced retinal pigmented epithelial-to-mesenchymal transition by the TGFb pathway inhibitor, A-83-01.

(Submitter supplied) Age-related macular degeneration (AMD) is a leading cause of blindness. Most vision loss occurs following the transition from a disease of deposit formation and inflammation to a disease of neovascular fibrosis and/or cell death. Here, we investigate how repeated wound stimulus leads to seminal changes in gene expression and the onset of a perpetual state of stimulus-independent wound response in retinal pigmented epithelial (RPE) cells, a cell-type central to the etiology of AMD. more...