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Items: 3

1.

Opposing roles for the lncRNA Haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation

(Submitter supplied) Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific lncRNAs, and the molecular mechanisms through which they act, remain unclear. Here, we demonstrate discrete and opposing roles for the lncRNA transcript Haunt and its genomic locus in regulating the HOXA gene cluster during ESC differentiation. Reducing or enhancing Haunt expression, with minimal disruption of the Haunt locus, led to up- or down-regulation of HOXA genes, respectively. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17021 GPL18480 GPL13112
54 Samples
Download data: BEDGRAPH, BIGWIG, TXT, XLSX
Series
Accession:
GSE58514
ID:
200058514
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

pKO-a_D2

Organism:
Mus musculus
Source name:
Haunt pKO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604237
ID:
301604237
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db=gds|term=GSM1604237[Accession]|query=1|qty=2|blobid=MCID_667ab5808c5d4760e22247c9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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