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Items: 3

1.

Prospective derivation of a 'Living Organoid Biobank' of colorectal cancer patients

(Submitter supplied) In Rspondin-based three-dimensional cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. Here we report the establishment of tumor organoid cultures from 20 consecutive colorectal carcinoma (CRC) patients. For most, organoids were also generated from adjacent normal tissue. Organoids closely resemble the original tumor. The spectrum of genetic changes within the 'living biobank' agrees well with previous large-scale mutational analyses of CRC. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
108 Samples
Download data: CSV
Series
Accession:
GSE65253
ID:
200065253
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Organoid 11 derived from patient 19a

Organism:
Homo sapiens
Source name:
Colonic Adenocarcinoma derived organoid
Platform:
GPL18573
Series:
GSE65253
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Sample
Accession:
GSM1590783
ID:
301590783
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