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Items: 3

1.

Insights into the combined action of SAHA (vorinostat) and Mithramycin A in Sézary cells through gene expression profiling

(Submitter supplied) Suberoyl Anilide Hydroxamic Acid (SAHA), also named under Vorinostat, is an inhibitor of class I and II histone deacetylases (HDACi) approved by the USA Food and Drug Administration (FDA) for the treatment of advanced and refractory cutaneous T-cell lymphomas (CTCL). Its limited efficacy led to its use in various combination therapies. Given that SAHA modifies the expression of many genes under control of Sp1 (or Sp3) transcription factors, we investigated here its association to the FDA-approved anticancer antibiotic Mithramycin (MitA), a direct inhibitor of the binding of Sp1 family factors to GC-rich DNA promoters. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13607
48 Samples
Download data: TXT
Series
Accession:
GSE64119
ID:
200064119
2.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Homo sapiens
233 Series
2 Related Platforms
3749 Samples
Download data: TXT
Platform
Accession:
GPL13607
ID:
100013607
3.

SS_P1 cells_Ctrl_rep.1

Organism:
Homo sapiens
Source name:
SS cells_no drug
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564735
ID:
301564735
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db=gds|term=GSM1564735[Accession]|query=1|qty=2|blobid=MCID_669e799756cb0a044edc5b31|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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