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Items: 4

1.

Genome-wide maps of chromatin state in LATS2-knockout HeLa-S3 cell

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
8 Samples
Download data: BW
Series
Accession:
GSE64072
ID:
200064072
2.

LATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by array; Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
36 Samples
Download data: BW, TXT
Series
Accession:
GSE63538
ID:
200063538
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

HeLa-S3_LATS2-/-_H3K27ac_ChIPSeq

Organism:
Homo sapiens
Source name:
LATS2-knockout HeLa-S3 cells
Platform:
GPL11154
Series:
GSE63538 GSE64072
Download data: BW
Sample
Accession:
GSM1563749
ID:
301563749
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