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Items: 4

1.

Transcriptome profiling of Lats2 deficient mouse embryonic fibroblasts

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
8 Samples
Download data: TXT
Series
Accession:
GSE63536
ID:
200063536
2.

LATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by array; Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
36 Samples
Download data: BW, TXT
Series
Accession:
GSE63538
ID:
200063538
3.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...
Organism:
Mus musculus
7 DataSets
600 Series
1 Related Platform
7479 Samples
Download data: TXT
Platform
Accession:
GPL4134
ID:
100004134
4.

MEF_Lats2KO_#121_rep2_dyeswap

Organism:
Mus musculus
Source name:
Embryonic fibroblast cells derived from LAT2+/+ C57BL/6J mice (channel 1) Embryonic fibroblast cells derived from LAT2-/- C57BL/6J mice (channel 2)
Platform:
GPL4134
Series:
GSE63536 GSE63538
Download data: TXT
Sample
Accession:
GSM1551897
ID:
301551897
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