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Items: 4

1.

Transcriptome profiling of HeLa-S3 cells treated with siRNAs targeting LATS1 and/or LATS2

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10332
4 Samples
Download data: TXT
Series
Accession:
GSE63533
ID:
200063533
2.

LATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by array; Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
36 Samples
Download data: BW, TXT
Series
Accession:
GSE63538
ID:
200063538
3.

Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Feature Number version)

(Submitter supplied) Human 44k Content Refresh Arrays of this design have barcodes that begin with 16026652 or 2526652. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Homo sapiens
186 Series
1 Related Platform
2217 Samples
Download data: TXT
Platform
Accession:
GPL10332
ID:
100010332
4.

HeLa-S3_siLATS1

Organism:
Homo sapiens
Source name:
HeLa-S3 cell, siLATS1
Platform:
GPL10332
Series:
GSE63533 GSE63538
Download data: TXT
Sample
Accession:
GSM1551880
ID:
301551880
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