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Items: 4

1.

Differentiation of acute myeloid leukemia cells

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL96 GPL80
117 Samples
Download data: CEL
Series
Accession:
GSE995
ID:
200000995
2.

Gene Expression-Based High Throughput Screening: APL Treatment with Candidate Compounds

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
24 Samples
Download data: CEL
Series
Accession:
GSE976
ID:
200000976
3.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
364 DataSets
1125 Series
11 Related Platforms
42430 Samples
Download data
Platform
Accession:
GPL96
ID:
100000096
4.

APL_Erythro2

Organism:
Homo sapiens
Source name:
primary APL cells treated with erythro-9-(2-hydroxy-3-nonyl) adenine HCl
Platform:
GPL96
Series:
GSE976 GSE995
Download data: CEL
Sample
Accession:
GSM15420
ID:
300015420
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