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Items: 3

1.

Cell-autonomous transformation of Lgr5-positive intestinal stem cells into gastric stem cells upon loss of transcription factor Cdx2

(Submitter supplied) Stomach and intestinal adult epithelia harbor stem cells that are responsible for their continuous regeneration. Stomach and intestinal stem cells differ in their differentiation program and in the gene repertoire that they express. We show that single adult Lgr5-positive stem cells, isolated from 3D cultured small intestinal organoids, require Cdx2 to maintain their intestinal identity and are converted cell-autonomously into stomach-pyloric stem cells in the absence of this transcription factor.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
16 Samples
Download data: TXT
Series
Accession:
GSE62784
ID:
200062784
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Extracted RNA from Control small intestine organoids Control_SI_1

Organism:
Mus musculus
Source name:
Extracted RNA from Control small intestine organoids
Platform:
GPL19057
Series:
GSE62784
Download data
Sample
Accession:
GSM1533379
ID:
301533379
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