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Items: 4

1.

T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
143 Samples
Download data: BED, GTF, TXT
Series
Accession:
GSE62486
ID:
200062486
2.

T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (Agilent 1)

(Submitter supplied) The transcription factor T-bet induces differentiation of CD4+ T cells into the Th1 lineage and also allows for a degree of functional plasticity. Here, we show that T-bet acts through super-enhancers to recruit the elongation factor P-TEFb. Th1-specific genes are poised for activation in Th2 cells and P-TEFb recruitment activates transcriptional elongation. T-bet also induces extensive P-TEFb binding at super-enhancers, where it acts to stimulate enhancer RNA transcription. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13607
23 Samples
Download data: TXT
Series
Accession:
GSE62484
ID:
200062484
3.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Homo sapiens
233 Series
2 Related Platforms
3749 Samples
Download data: TXT
Platform
Accession:
GPL13607
ID:
100013607
4.

Donor3 day 7 Th2 unactivated

Organism:
Homo sapiens
Source name:
Th2 (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL13607
Series:
GSE62484 GSE62486
Download data: TXT
Sample
Accession:
GSM1527754
ID:
301527754
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