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Items: 4

1.

Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19251 GPL11154 GPL10739
137 Samples
Download data: BW, CEL, CHP
Series
Accession:
GSE62246
ID:
200062246
2.

Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (array)

(Submitter supplied) Most B cell lymphomas arise in the germinal center (GC), where humoral immune responses evolve from potentially oncogenic cycles of mutation, proliferation, and clonal selection. Although lymphoma gene expression diverges significantly from GC-B cells, underlying mechanisms that alter the activities of corresponding regulatory elements (REs) remain elusive. Here we define the complete pathogenic circuitry of human follicular lymphoma (FL), which activates or decommissions transcriptional circuits from normal GC-B cells and commandeers enhancers from other lineages. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL10739 GPL19251
30 Samples
Download data: CEL, CHP
Series
Accession:
GSE61912
ID:
200061912
3.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [probe set (exon) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Thu Jan 21 16:38:27 2010 PST #%chip_type=HuGene-1_0-st-v1 #%lib_set_name=HuGene-1_0-st #%lib_set_version=v1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%netaffx-annotation-date=2009-11-23 #%netaffx-annotation-netaffx-build=30.1 Protocol: See manufacturer's web site
Organism:
Homo sapiens
57 Series
664 Samples
Download data
Platform
Accession:
GPL10739
ID:
100010739
4.

FL7_mRNA

Organism:
Homo sapiens
Source name:
CD19+ B cells
Platform:
GPL10739
Series:
GSE61912 GSE62246
Download data: CEL, CHP
Sample
Accession:
GSM1517161
ID:
301517161
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