U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

Divergent transcriptional activation by glucocorticoids in mouse and human macrophages is the result of gain and loss of enhancers

(Submitter supplied) Macrophages are amongst the major targets of glucocorticoids (GC) as therapeutic anti-inflammatory agents. Here we show that GC treatment of mouse and human macrophages initiates a cascade of induced gene expression including many anti-inflammatory genes. Inducible binding of the glucocorticoid receptor (GR) was detected at candidate enhancers in the vicinity of induced genes in both species and this was strongly associated with canonical GR binding motifs. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
52 Samples
Download data: CEL
Series
Accession:
GSE61881
ID:
200061881
2.

Expression response of human monocyte derived macrophages to dexamethasone over a 24h time series

(Submitter supplied) Macrophages are amongst the major targets of glucocorticoids (GC) as therapeutic anti-inflammatory agents. Here we show that GC treatment of mouse and human macrophages initiates a cascade of induced gene expression including many anti-inflammatory genes. Inducible binding of the glucocorticoid receptor (GR) was detected at candidate enhancers in the vicinity of induced genes in both species and this was strongly associated with canonical GR binding motifs. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13158
24 Samples
Download data: CEL
Series
Accession:
GSE61880
ID:
200061880
3.

[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Annotations derived from HT_HG-U133_Plus_PM.na31.annot.csv Protocol: see manufacturer's web site
Organism:
Homo sapiens
2 DataSets
153 Series
4 Related Platforms
14616 Samples
Download data
Platform
Accession:
GPL13158
ID:
100013158
4.

MDM-2h-dex100nM-rep1

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516154
ID:
301516154
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM1516154[Accession]|query=1|qty=3|blobid=MCID_66a2254657bd0c119091524a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center