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Items: 4

1.

Physical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL16791
6 Samples
Download data: BED, TXT
Series
Accession:
GSE65474
ID:
200065474
2.

Physical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution [ChIP-seq]

(Submitter supplied) Senescence of stromal fibroblasts has been linked to establishment of cancer associated fibroblasts (CAF) and aging-associated increase of tumors. However, in clinically occurring carcinomas, density and proliferation of CAFs are frequently increased rather than decreased. We previously showed that genetic deletion or down-modulation of the canonical Notch effector CSL/RBP-Jκ in skin dermal fibroblasts is sufficient for CAF activation with consequent development of multifocal keratinocyte tumors. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
3 Samples
Download data: BED
Series
Accession:
GSE59942
ID:
200059942
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

Input DNA

Organism:
Homo sapiens
Source name:
primary dermal fibroblasts
Platform:
GPL11154
Series:
GSE59942 GSE65474
Download data
Sample
Accession:
GSM1462554
ID:
301462554
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Supplemental Content

db=gds|term=GSM1462554[Accession]|query=1|qty=2|blobid=MCID_66291ff8862bea0a3fa1a0f9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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