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Items: 3

1.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

(Submitter supplied) BACKGROUND: Glioma stem cells (GSCs) from human glioblastomas (GBMs) are resistant to radiation and chemotherapy and may drive recurrence. Treatment efficacy may depend on GSCs, expression of DNA repair enzymes such as methylguanine methyltransferase (MGMT), or transcriptome subtype. METHODS: To model genetic alterations in human GBM core signaling pathways, we induced Rb knockout, Kras activation, and Pten deletion mutations in cortical murine astrocytes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
37 Samples
Download data: TXT
Series
Accession:
GSE59116
ID:
200059116
2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
334 Series
1 Related Platform
4120 Samples
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Platform
Accession:
GPL11202
ID:
100011202
3.

T_243533

Organism:
Mus musculus
Source name:
TRP allograft tumor_untreated (channel 1) Stratagene whole mouse reference RNA (channel 2)
Platform:
GPL11202
Series:
GSE59116
Download data: TXT
Sample
Accession:
GSM1428864
ID:
301428864
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db=gds|term=GSM1428864[Accession]|query=1|qty=2|blobid=MCID_66556c336c05354989c7b9ea|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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