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Items: 4

1.

ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL11154
30 Samples
Download data: BED, RPKM, WIG
Series
Accession:
GSE59090
ID:
200059090
2.

ChIP-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells

(Submitter supplied) Polycomb Repressive Complex 2 (PRC2) plays crucial roles in transcriptional regulation and stem cell development. However, the context-specific functions associated with alternative subunits remain largely unexplored. Here we show that the related enzymatic subunits EZH1 and EZH2 undergo an expression switch during hematopoiesis. We examine the in vivo stoichiometry of the PRC2 complexes by quantitative proteomics and reveal the existence of an EZH1-SUZ12 sub-complex lacking EED. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
15 Samples
Download data: BED, WIG
Series
Accession:
GSE59087
ID:
200059087
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

SUZ12

Organism:
Homo sapiens
Source name:
Human primary fetal liver proerythroblasts (ProEs), SUZ12 ChIP
Platform:
GPL11154
Series:
GSE59087 GSE59090
Download data: BED, WIG
Sample
Accession:
GSM1427067
ID:
301427067
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Supplemental Content

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