GSM1395381[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000578711.

RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of GLI1 or PSMD13 with or without vorinostat treatment

(Submitter supplied) Transcriptome analysis was conducted on vorinostat resistant HCT116 cells (HCT116-VR) upon knockdown of potential vorinostat resistance candidate genes in the presence and absence of vorinostat. Potential vorinostat resistance candidate genes chosen for this study were GLI1 and PSMD13, which were identified through a genome-wide synthetic lethal RNA interference screen. To understand the transcriptional events underpinning the effect of GLI1 and PSMD13 knockdown (sensitisation to vorinostat-induced apoptosis), cells were first subjected to gene knockdown, then to treatment with vorinsotat or the solvent control. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
42 Samples

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Series

Accession:: GSE57871

ID:: 200057871

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000167912.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12246 Series
350070 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3013953813.

siPSMD13_DMSO_8hr rep2

Organism:: Homo sapiens

Source name:: colorectal carcinoma cell line

Platform:: GPL16791
Series:: GSE57871

Sample

Accession:: GSM1395381

ID:: 301395381

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GSM1395381[Accession] (3)
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