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Items: 4

1.

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by array
Platforms:
GPL4133 GPL13534
575 Samples
Download data: TXT
Series
Accession:
GSE57343
ID:
200057343
2.

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers [methylation]

(Submitter supplied) Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidine (AZA). Gene Set Enrichment Analysis demonstrated significant enrichment for immunomodulatory pathways in all three cancers (14.4-31.3%) including interferon signaling, antigen processing and presentation, and cytokines/chemokines. more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
338 Samples
Download data: TXT
Series
Accession:
GSE57342
ID:
200057342
3.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website
Organism:
Homo sapiens
1684 Series
1 Related Platform
119076 Samples
Download data: BPM, CSV, TXT, XLSX
Platform
Accession:
GPL13534
ID:
100013534
4.

genomic dna from breast_EFM19_Mock_Day3

Organism:
Homo sapiens
Source name:
breast_EFM19_Mock
Platform:
GPL13534
Series:
GSE57342 GSE57343
Download data
Sample
Accession:
GSM1380422
ID:
301380422
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