GSM1322794[Accession] - GEO DataSets

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Items: 4

Select item 2000547211.

DNA methylation changes at CpG and non-CpG sites are associated with development and clinical behavior in neuroblastoma.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array; Expression profiling by array

Platforms:: GPL13667 GPL13534
64 Samples

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Accession:: GSE54721

ID:: 200054721

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000547202.

DNA methylation changes at CpG and non-CpG sites are associated with development and clinical behavior in neuroblastoma [gene expression]

(Submitter supplied) DNA methylation changes in neuroblastoma, a clinically-heterogeneous pediatric tumor, have been described essentially in promoter regions. We analyzed the DNA methylome of neuroblastoma using high-density microarrays and observed differential methylation not only in promoters but also in intragenic and intergenic regions at both CpG and non-CpG sites. These epigenetic changes showed a non-random distribution relative functional chromatin domains, and targeted development and cancer-related genes, relevant for neuroblastoma pathogenesis. more...