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Items: 4

1.

Genome-wide and single-cell analyses reveal target gene context-dependent relationship between Crebbp recruitment and both constitutive and signal-responsive gene expression.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11180 GPL11002
20 Samples
Download data: BW, CEL
Series
Accession:
GSE54454
ID:
200054454
2.

Expression data from wild type and CBP/p300 null MEFs +/- 3hr treatment with 100uM dipyridyl (DP)

(Submitter supplied) Genome-wide distribution of histone H3K18 and H3K27 acetyltransferases, Crebbp (CBP) and Ep300 (p300), is used to map enhancers and promoters, but whether these elements functionally require CBP/p300 remains largely uncertain. We investigated this relationship by comparing genomic CBP recruitment with gene expression in wild type and CBP/p300 double-knockout fibroblasts. ChIP-seq revealed nearby CBP recruitment for 20 percent of constitutively expressed genes, but surprisingly, three-quarters of these were unaffected or slightly activated by CBP/p300 deletion. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11180
12 Samples
Download data: CEL
Series
Accession:
GSE54452
ID:
200054452
3.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site
Organism:
Mus musculus
13 DataSets
285 Series
9 Related Platforms
6973 Samples
Download data
Platform
Accession:
GPL11180
ID:
100011180
4.

dKO6E

Organism:
Mus musculus
Source name:
CBP/p300 null MEF 6, 3hr EtOH
Platform:
GPL11180
Series:
GSE54452 GSE54454
Download data: CEL
Sample
Accession:
GSM1315593
ID:
301315593
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