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Items: 4

1.

Aberrant chromatin acetylation in MLL-AF9 leukemia mediates the response to HDAC inhibition

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10999 GPL17077
25 Samples
Download data: BED, TXT, WIG
Series
Accession:
GSE54348
ID:
200054348
2.

Aberrant chromatin acetylation in MLL-AF9 leukemia mediates the response to HDAC inhibition (microarray)

(Submitter supplied) We investigated the response of acute myeloid cells (AML) expressing MLL-AF9 fusion gene to the pan-HDACi panobinostat (LBH589), and found that low conentrations of panobinostat lead to MLL-AF9 cell toxicity and rapid changes in gene expression. Human hematopoietic stem/progenitor cells (HSPC) expressing MLL-AF9 fusion protein (Wei et al, Cancer Cell 2008) were cultured with 30 nM panobinostat during 6 and 24 hours. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
16 Samples
Download data: TXT
Series
Accession:
GSE54218
ID:
200054218
3.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...
Organism:
Homo sapiens
572 Series
1 Related Platform
9505 Samples
Download data
Platform
Accession:
GPL17077
ID:
100017077
4.

HSPC-MA9.31_untreated_rep1

Organism:
Homo sapiens
Source name:
CD34+ cord blood cells transduced with MLL-AF9 fusion gene
Platform:
GPL17077
Series:
GSE54218 GSE54348
Download data: TXT
Sample
Accession:
GSM1310391
ID:
301310391
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