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Items: 3

1.

Retinoic acid induced changes in gene expression in TAF4 knock out fibroblasts

(Submitter supplied) Collagen 6A3 (Col6a3), a component of extracellular matrix, is often up-regulated in tumours and is believed to play a pro-oncogenic role. However the mechanisms of its tumorigenic activity are poorly understood. We show here that Col6a3 is highly expressed in densely growing mouse embryonic fibroblasts (MEFs). In MEFs where the TAF4 subunit of general transcription factor IID (TFIID) has been inactivated, elevated Col6a3 expression prevents contact inhibition promoting their 3 dimensional growth as foci and fibrospheres. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11002
8 Samples
Download data: TSV
Series
Accession:
GSE53097
ID:
200053097
2.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
3.

ARN_cl1_RA_12h_rep3

Organism:
Mus musculus
Source name:
TAF4-/- immortalized mouse embryonic fibroblasts.
Platform:
GPL11002
Series:
GSE53097
Download data
Sample
Accession:
GSM1282339
ID:
301282339
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