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Items: 3

1.

Pseudo-temporal ordering of individual cells reveals regulators of differentiation

(Submitter supplied) Single-cell expression profiling by RNA-Seq promises to exploit cell-to-cell variation in gene expression to reveal regulatory circuitry governing cell differentiation and other biological processes. Here, we describe Monocle, a novel unsupervised algorithm for ordering cells by progress through differentiation that dramatically increases temporal resolution of expression measurements. This reordering unmasks switch-like changes in expression of key regulatory factors, reveals sequentially organized waves of gene regulation, and exposes regulators of cell differentiation. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL16791
384 Samples
Download data: TXT
Series
Accession:
GSE52529
ID:
200052529
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

Cell T0_CT_E04

Organism:
Homo sapiens
Source name:
Myoblast_Cell T0_CT_E
Platform:
GPL16791
Series:
GSE52529
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Sample
Accession:
GSM1269011
ID:
301269011
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