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Items: 3

1.

Epigenetic and transcriptional landscapes of Dnmt3a-deficient olfactory sensory neurons

(Submitter supplied) During differentiation, neurons experience a reorganization of DNA modification patterns within their genomes. However, the mechanisms underlying this developmental patterning and its role in defining the neurona­­l state are currently unclear. Here, we find that the d­­e novo DNA methyltransferase Dnmt3a is necessary for elevated levels of 5-hydroxymethylcytosine (5hmC), a derivative of 5-methylcytosine (5mC), in olfactory sensory neurons (OSNs). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL17021 GPL13112
33 Samples
Download data: TXT, WIG
Series
Accession:
GSE52464
ID:
200052464
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

Dnmt3a +/+ MOE H3K27me3 rep1

Organism:
Mus musculus
Source name:
main olfactory epithelium
Platform:
GPL17021
Series:
GSE52464
Download data: WIG
Sample
Accession:
GSM1267291
ID:
301267291
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Supplemental Content

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