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Items: 3

1.

The effect of inhaled IFNbeta (SNG001) versus placebo on peripheral blood mononuclear cells during an upper respiratory tract infection

(Submitter supplied) Microarray analysis of whole blood samples (collected into PAXgene tubes from PreAnalytiX) during a phase II double-blind, randomized (1:1 ratio) clinical trial in which inhaled IFN-β (SNG001) or placebo treatment was initiated within 24 hours of asthmatics reporting cold symptoms. Patients were dosed once a day for 14 days, with samples collected at day 1 (prior to first dose), day 4 and day 7. Analysis of genome-wide gene expression (only conducted using samples from the BTS Step 4/5, mITT subgroup), showed a treatment-related enhancement of systemic innate immunity, thereby providing compelling evidence for exogenous IFN-β enhancing antiviral responses.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
141 Samples
Download data: TXT
Series
Accession:
GSE50943
ID:
200050943
2.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...
Organism:
Homo sapiens
577 Series
1 Related Platform
9541 Samples
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Platform
Accession:
GPL17077
ID:
100017077
3.

PBMC_SNG001_visit2_rep16

Organism:
Homo sapiens
Source name:
Peripheral blood mononuclear cells, SNG001 (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE50943
Download data: TXT
Sample
Accession:
GSM1232897
ID:
301232897
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db=gds|term=GSM1232897[Accession]|query=1|qty=2|blobid=MCID_67575dd779cb8359a29863e5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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