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Items: 3

1.

c-Jun impedes somatic cell reprogramming by activating mesenchymal core regulators and suppressing pluripotent ones

(Submitter supplied) The somatic cell fate can be converted to tumor or pluripotent ones by ectopic expression of transcription factors in vitro and in vivo. Many oncogenic transcription factors are known to mediate both fates as they share similar proliferative and metabolic properties. Paradoxically, we found c-Jun as the first oncogene that appears to specify a somatic fate, oppose the pluripotent one and impede reprogramming. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL16417 GPL13112
16 Samples
Download data: TXT, XLS
Series
Accession:
GSE50776
ID:
200050776
2.

Illumina MiSeq (Mus musculus)

Platform
Accession:
GPL16417
ID:
100016417
3.

MEF_c-Jun

Organism:
Mus musculus
Source name:
mouse embryonic fibroblasts (MEFs)
Platform:
GPL16417
Series:
GSE50776
Download data: TXT
Sample
Accession:
GSM1229028
ID:
301229028
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