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Items: 3

1.

After demyelination in the adult CNS, oligodendrocyte precursor cells revert to an immature mRNA profile and express immune cues favoring their migration

(Submitter supplied) In multiple sclerosis (MS) and experimental models of demyelination, myelin repair is mostly achieved by oligodendrocyte precursor cells (OPCs). To gain insight into the biological specificity of these adult precursors, in the perspective to better understand why remyelination often fails in MS, we performed a micro-array analysis on purified populations of murine OPCs and oligodendrocytes. We demonstrated that, in a control environment, “quiescent” adult OPCs are more mature than neonatal OPCs, with a mRNA profile closer to oligodendrocytes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
18 Samples
Download data: TXT
Series
Accession:
GSE48872
ID:
200048872
2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
333 Series
1 Related Platform
4118 Samples
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Platform
Accession:
GPL11202
ID:
100011202
3.

adult progenitor of oligodendrocytes from control brains_rep3

Organism:
Mus musculus
Source name:
adult progenitor of oligodendrocytes from control brains
Platform:
GPL11202
Series:
GSE48872
Download data: TXT
Sample
Accession:
GSM1186210
ID:
301186210
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