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Items: 4

1.

The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL16417 GPL4134
8 Samples
Download data: BW, TXT
Series
Accession:
GSE51534
ID:
200051534
2.

The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (RNA-IP)

(Submitter supplied) Embryonic stem cell (ESC) self-renewal and differentiation is governed by a comprehensive regulatory network. Although the transcriptional regulation has been extensively investigated, post-transcriptional mechanisms controlling the ESC state are poorly understood. Here we describe a critical role of the THO complex in ESC self-renewal and differentiation. We show that THO preferentially interacts with pluripotency gene transcripts through Thoc5, and is required for self-renewal by regulating their export and expression. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16417
2 Samples
Download data: BW
Series
Accession:
GSE48436
ID:
200048436
3.

Illumina MiSeq (Mus musculus)

Platform
Accession:
GPL16417
ID:
100016417
4.

Input

Organism:
Mus musculus
Source name:
J1_input
Platform:
GPL16417
Series:
GSE48436 GSE51534
Download data: BW
Sample
Accession:
GSM1178724
ID:
301178724
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Supplemental Content

db=gds|term=GSM1178724[Accession]|query=1|qty=2|blobid=MCID_6654b3146c05354989b469ea|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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