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Items: 4

1.

Orchestrated intron retention regulates normal granulocyte differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL6246 GPL11002 GPL10999
11 Samples
Download data: CEL, GTF
Series
Accession:
GSE48307
ID:
200048307
2.

Orchestrated intron retention regulates normal granulocyte differentiation [RNA-Seq]

(Submitter supplied) Using mRNA-seq, we determined intron retaining genes that were differentially regulated in FACS purified cells at three progressive stages of mouse granulopoiesis; CD34+Kit+Gr-1low promyelocytes, CD34-Kit-Gr-1mid myelocytes and CD34-Kit-Gr-1high granulocytes. We found that IR affects 86 genes, including those specific to granulocyte (Lyz2 and MMP8) and nuclear architecture (Lmnb1 and Lbr). IR was associated with the decrease in protein levels measured by mass spectrometry (P=0.0015, binomial test). more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11002 GPL10999
5 Samples
Download data: GTF
Series
Accession:
GSE48305
ID:
200048305
3.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
4.

promyelocytes

Organism:
Mus musculus
Source name:
promyelocytes
Platform:
GPL11002
Series:
GSE48305 GSE48307
Download data: GTF
Sample
Accession:
GSM1174469
ID:
301174469
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Supplemental Content

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