GSM1160031[Accession] - GEO DataSets

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Items: 4

Select item 2000478191.

Epigenetic and genetic changes during mouse hematopoietic stem cell aging

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL13112
37 Samples

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Series

Accession:: GSE47819

ID:: 200047819

PubMed Full text in PMC Similar studies

Select item 2000478172.

Epigenetic and genetic changes during mouse hematopoietic stem cell aging [RNA-Seq]

(Submitter supplied) To investigate the global transcriptome changes in mouse hematopoietic stem cell aging, we performed high-throughput sequencing of Poly A+ RNA (RNA-Seq) from purified 4 month, and 24 month-old HSCs (SP-KSL-CD150+). With biological duplicates, more than 200 million reads in total for each age of HSC were obtained. Comparison of the young and old HSC transcriptomes revealed that 1,337 genes that were up-regulated, and 1,297 genes were down-regulated with HSC aging. more...