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Items: 3

1.

Genome-wide Genotyping of Acute Myeloid Leukemia with Translocation t(9;11)(p22;q23) Reveals Novel Recurrent Genomic Alterations

(Submitter supplied) To identify cooperating lesions in de novo and therapy-related acute myeloid leukemia (t-AML) with translocation t(9;11)(p22;q23) we performed high-resolution SNP-array profiling on 40 leukemia samples [de novo: n=22; t-AML: n=16; unknown: n=2]. A mean of 1.73 copy number alterations (CNAs)/case were identified with no differences between de novo and t-AML cases. We identified a novel minimally deleted region (MDR) at 7q36.1-q36.2 partly overlapping with a MDR previously identified in core-binding factor AML; MLL3 was the only gene affected in both regions. more...
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platform:
GPL6801
55 Samples
Download data: CEL, CHP
Series
Accession:
GSE46745
ID:
200046745
2.

[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 (ucsc=hg18; ncbi=NCBI36) August 01, 2012: annotation table updated with netaffx build 32 (ucsc=hg19; ncbi=GRCh37) Protocol: see manufacturer's web site The new Affymetrix® Genome-Wide Human SNP Array 6.0 features 1.8 million genetic markers, including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation. more...
Organism:
Homo sapiens
404 Series
22859 Samples
Download data
Platform
Accession:
GPL6801
ID:
100006801
3.

MLL#20

Organism:
Homo sapiens
Source name:
Leukemic cells obtained from bone marrow or blood at diagnosis
Platform:
GPL6801
Series:
GSE46745
Download data: CEL, CHP
Sample
Accession:
GSM1138078
ID:
301138078
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