U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 3

1.

ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation

(Submitter supplied) T follicular helper (Tfh) cells are essential in the induction of high-affinity, class-switched antibodies. The differentiation of Tfh cells is a multi-step process that depends upon the co-receptor ICOS and the activation of phosphoinositide-3 kinase leading to the expression of key Tfh cell genes. We report that ICOS signaling inactivates the transcription factor FOXO1, and a Foxo1 genetic deletion allowed for generation of Tfh cells with reduced dependence on ICOS ligand. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
6 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE46525
ID:
200046525
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

naiveT_foxo1_ChIPseq

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL13112
Series:
GSE46525
Download data: BED, BEDGRAPH
Sample
Accession:
GSM1131775
ID:
301131775
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM1131775[Accession]|query=1|qty=2|blobid=MCID_65e1f62d0b2ad618bb713af3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center