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Items: 3

1.

Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.

(Submitter supplied) The degradation of TNFα mRNA is critical for restricting TNFα synthesis and involves a constitutive decay element (CDE) in the 3’ untranslated region of the mRNA. We demonstrate that the active CDE is a stem-loop RNA motif that is recognized by the RNA-binding protein Roquin. Deep sequencing of Roquin-associated mRNAs identified CDE-containing mRNAs as the primary targets of Roquin on a transcriptome-wide scale.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
9 Samples
Download data: TXT
Series
Accession:
GSE44775
ID:
200044775
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Input3

Organism:
Mus musculus
Source name:
RAW264.7_Input
Platform:
GPL13112
Series:
GSE44775
Download data
Sample
Accession:
GSM1090979
ID:
301090979
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db=gds|term=GSM1090979[Accession]|query=1|qty=2|blobid=MCID_65d79d518e7da52507dc268f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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