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Items: 3

1.

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

(Submitter supplied) Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial self-renewal. Here we show that p63 expression is suppressed by Notch1 activation in both mouse and human keratinocytes through a mechanism independent of cell cycle withdrawal and requiring down-modulation of selected interferon-responsive genes, including IRF7 and/or IRF3. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL339 GPL571
4 Samples
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Series
Accession:
GSE5229
ID:
200005229
2.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
638 Series
12 Related Platforms
24352 Samples
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Platform
Accession:
GPL571
ID:
100000571
3.

Human Keratinocytes Ad-Notch1

Organism:
Homo sapiens
Source name:
Human keratinocytes
Platform:
GPL571
Series:
GSE5229
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Sample
Accession:
GSM108473
ID:
300108473
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db=gds|term=GSM108473[Accession]|query=1|qty=3|blobid=MCID_666e7b966e9d376f23595402|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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