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Items: 4

1.

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array; Other
4 related Platforms
52 Samples
Download data: BED, BW, CEL, TXT
Series
Accession:
GSE44163
ID:
200044163
2.

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [RNA-seq_siRNA_transfection]

(Submitter supplied) MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with increases in transcription. Direct and indirect targets of this miRNA belong to a mid-gestation embryonic program that encompasses known oncofetal genes as well as oncogenes not previously associated with an embryonic state. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
12 Samples
Download data: TXT
Series
Accession:
GSE44157
ID:
200044157
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

WT_siCtrl_R2

Organism:
Mus musculus
Source name:
Dicer f/f murine MSC cell line
Platform:
GPL13112
Series:
GSE44157 GSE44163
Download data
Sample
Accession:
GSM1079787
ID:
301079787
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