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Items: 3

1.

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system

(Submitter supplied) The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the central nervous system (CNS) may differ from those present in embryonic stem cells. Here we present quantitative, genome-wide analysis of 5hmC, 5- methylcytosine (5mC) and gene expression in differentiated CNS cell types in vivo. We report that 5hmC is enriched in active genes, and that surprisingly strong depletion of 5mC is observed over these regions. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
Platforms:
GPL13112 GPL9250
50 Samples
Download data: BEDGRAPH, WIG
Series
Accession:
GSE42880
ID:
200042880
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Input Cerebellum tissue for sept4 TRAPSeq male 2

Organism:
Mus musculus
Source name:
Cerebellum
Platform:
GPL13112
Series:
GSE42880
Download data: WIG
Sample
Accession:
GSM1063334
ID:
301063334
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Supplemental Content

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