GSM1054198[Accession] - GEO DataSets

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Items: 3

Select item 2000429751.

Novel dedifferentiated liposarcoma xenograft models reveal PTEN down regulation as a malignant signature and response to PI3K pathway inhibition

(Submitter supplied) Liposarcoma is a type of soft tissue sarcoma, exhibiting poor survival and a high recurrence rate. Treatment is generally limited to surgery and radiation, emphasizing the need to understand this disease. Because very few in vivo and in vitro models can reproducibly recapitulate the human disease, we generated several xenograft models from surgically resected human dedifferentiated liposarcoma. Our study demonstrates that all xenografts recapitulate morphologic and gene expression characteristics of the patient tumors after continuous in vivo passages. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL13607 GPL6480
30 Samples

Download data: TXT

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Accession:: GSE42975

ID:: 200042975

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000064802.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...