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Items: 3

1.

Novel dedifferentiated liposarcoma xenograft models reveal PTEN down regulation as a malignant signature and response to PI3K pathway inhibition

(Submitter supplied) Liposarcoma is a type of soft tissue sarcoma, exhibiting poor survival and a high recurrence rate. Treatment is generally limited to surgery and radiation, emphasizing the need to understand this disease. Because very few in vivo and in vitro models can reproducibly recapitulate the human disease, we generated several xenograft models from surgically resected human dedifferentiated liposarcoma. Our study demonstrates that all xenografts recapitulate morphologic and gene expression characteristics of the patient tumors after continuous in vivo passages. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL13607 GPL6480
30 Samples
Download data: TXT
Series
Accession:
GSE42975
ID:
200042975
2.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
21 DataSets
941 Series
4 Related Platforms
24800 Samples
Download data
Platform
Accession:
GPL6480
ID:
100006480
3.

LPSX3 Xenograft passage 16

Organism:
Homo sapiens
Source name:
Mixed reference pool of fatty tumors (channel 1) LPSX3 Xenograft passage 16 (channel 2)
Platform:
GPL6480
Series:
GSE42975
Download data: TXT
Sample
Accession:
GSM1054198
ID:
301054198
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