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Items: 3

1.

Genome-wide profiling of 5-Formylcytosine reveals it roles in epigenetic priming

(Submitter supplied) TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC are excised by mammalian DNA glycosylase TDG, implicating 5mC oxidation in DNA demethylation. Here we show that the genomic locations of 5fC can be determined by coupling chemical reduction with biotin tagging. Genome-wide mapping of 5fC in mouse embryonic stem cells (mESCs) reveals that 5fC preferentially occurs at poised enhancers among other gene regulatory elements. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL16173 GPL13112
30 Samples
Download data: BED, TXT
Series
Accession:
GSE41545
ID:
200041545
2.

Illumina HiScanSQ (Mus musculus)

Organism:
Mus musculus
76 Series
652 Samples
Download data
Platform
Accession:
GPL16173
ID:
100016173
3.

p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate a

Organism:
Mus musculus
Source name:
p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate a
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019080
ID:
301019080
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Supplemental Content

db=gds|term=GSM1019080[Accession]|query=1|qty=2|blobid=MCID_6657aef76c0535498908d850|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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